The rapid emergence of infectious disease outbreaks has underscored the urgent need for effective communication tools to manage public health crises. Artificial Intelligence (AI)-based chatbots have become increasingly important in these situations, serving as critical resources to provide immediate and reliable information. This review examines the role of AI-based chatbots in public health emergencies, particularly during infectious disease outbreaks. By providing real-time responses to public inquiries, these chatbots help disseminate accurate information, correct misinformation, and reduce public anxiety. Furthermore, AI chatbots play a vital role in supporting healthcare systems by triaging inquiries, offering guidance on symptoms and preventive measures, and directing users to appropriate health services. This not only enhances public access to critical information but also helps alleviate the workload of healthcare professionals, allowing them to focus on more complex tasks. However, the implementation of AI-based chatbots is not without challenges. Issues such as the accuracy of information, user trust, and ethical considerations regarding data privacy are critical factors that need to be addressed to optimize their effectiveness. Additionally, the adaptability of these chatbots to rapidly evolving health scenarios is essential for their sustained relevance. Despite these challenges, the potential of AI-driven chatbots to transform public health communication during emergencies is significant. This review highlights the importance of continuous development and the integration of AI chatbots into public health strategies to enhance preparedness and response efforts during infectious disease outbreaks. Their role in providing accessible, accurate, and timely information makes them indispensable tools in modern public health emergency management.